IKZF3 (NM_012481) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC207547L1V
- LentiORF®
Lenti ORF particles, IKZF3 (Myc-DDK tagged) - Human IKAROS family zinc finger 3 (Aiolos) (IKZF3), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro mGFP mGFP w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | IKZF3 |
Synonyms | AIO; AIOLOS; ZNFN1A3 |
Mammalian Cell Selection | None |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_012481 |
ORF Size | 1527 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207547).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012481.3 |
RefSeq Size | 9686 bp |
RefSeq ORF | 1530 bp |
Locus ID | 22806 |
UniProt ID | Q9UKT9 |
Cytogenetics | 17q12-q21.1 |
MW | 58 kDa |
Gene Summary | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] |
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