GNMT (NM_018960) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207497L1V

Lenti ORF particles, GNMT (Myc-DDK tagged) - Human glycine N-methyltransferase (GNMT), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GNMT
• Synonyms: HEL-S-182mP
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_018960
• ORF Size: 885 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207497).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018960.4
• RefSeq Size: 1091 bp
• RefSeq ORF: 888 bp
• Locus ID: 27232
• UniProt ID: Q14749
• Cytogenetics: 6p21.1
• Protein Families: Druggable Genome
• Protein Pathways: Glycine, serine and threonine metabolism
• MW: 32.7 kDa
• Gene Summary: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]