GCLM (NM_002061) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207224L1V

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  • LentiORF®

Lenti ORF particles, GCLM (Myc-DDK tagged) - Human glutamate-cysteine ligase, modifier subunit (GCLM), 200ul, >10^7 TU/mL



USD 850.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name GCLM (NM_002061) Human Tagged ORF Clone Lentiviral Particle
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol GCLM
Synonyms GLCLR
Vector pLenti-C-Myc-DDK
ACCN NM_002061
ORF Size 822 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC207224).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002061.2, NP_002052.1
RefSeq Size 3074 bp
RefSeq ORF 825 bp
Locus ID 2730
Cytogenetics 1p22.1
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism, Metabolic pathways
MW 30.7 kDa
Gene Summary Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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