Islet 1 (ISL1) (NM_002202) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206893L3V

Lenti ORF particles, ISL1 (Myc-DDK tagged) - Human ISL LIM homeobox 1 (ISL1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Islet 1
• Synonyms: Isl-1; ISLET1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_002202
• ORF Size: 1047 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206893).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002202.2, NP_002193.2
• RefSeq Size: 2729 bp
• RefSeq ORF: 1050 bp
• Locus ID: 3670
• UniProt ID: P61371
• Cytogenetics: 5q11.1
• Protein Families: ES Cell Differentiation/IPS, Transcription Factors
• MW: 39 kDa
• Gene Summary: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]