CDC6 (NM_001254) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206814L4V

Lenti ORF particles, CDC6 (mGFP-tagged) - Human cell division cycle 6 homolog (S. cerevisiae) (CDC6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CDC6
• Synonyms: CDC18L; HsCDC6; HsCDC18; MGORS5
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001254
• ORF Size: 1680 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206814).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001254.3
• RefSeq Size: 3053 bp
• RefSeq ORF: 1683 bp
• Locus ID: 990
• UniProt ID: Q99741
• Cytogenetics: 17q21.2
• Domains: AAA, AAA
• Protein Pathways: Cell cycle
• MW: 62.7 kDa
• Gene Summary: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]