alpha 1 Fetoprotein (AFP) (NM_001134) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206622L1V

  • LentiORF®

Lenti ORF particles, AFP (Myc-DDK tagged) - Human alpha-fetoprotein (AFP), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


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USD 1,117.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol alpha 1 Fetoprotein
Synonyms AFPD; FETA; HPAFP
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_001134
ORF Size 1827 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC206622).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001134.1
RefSeq Size 2057 bp
RefSeq ORF 1830 bp
Locus ID 174
UniProt ID P02771
Cytogenetics 4q13.3
Protein Families Druggable Genome, Secreted Protein
MW 68.7 kDa
Gene Summary This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]

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