HSD17B3 (NM_000197) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206558L1V

Lenti ORF particles, HSD17B3 (Myc-DDK tagged) - Human hydroxysteroid (17-beta) dehydrogenase 3 (HSD17B3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: HSD17B3
• Synonyms: EDH17B3; SDR12C2
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000197
• ORF Size: 930 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206558).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000197.1
• RefSeq Size: 1134 bp
• RefSeq ORF: 933 bp
• Locus ID: 3293
• UniProt ID: P37058
• Cytogenetics: 9q22.32
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, Metabolic pathways
• MW: 34.5 kDa
• Gene Summary: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]