CD4 (NM_000616) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206453L3V

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  • LentiORF®

Lenti ORF particles, CD4 (Myc-DDK tagged) - Human CD4 molecule (CD4), transcript variant 1, 200ul, >10^7 TU/mL



USD 1,007.00

2 Weeks*

Size
    • 200 ul

Product images

Frequently bought together (2)
Lenti ORF control particles of pLenti-C-Myc-DDK-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
    • 500 ul

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One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA
    • 96 reactions

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol CD4
Synonyms CD4mut; IMD79; OKT4D
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_000616
ORF Size 1374 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC206453).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000616.2, NP_000607.1
RefSeq Size 3134 bp
RefSeq ORF 1377 bp
Locus ID 920
UniProt ID P01730
Cytogenetics 12p13.31
Domains ig, IGv, IGc2, IG
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
MW 51.1 kDa
Gene Summary This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.