Glutaminase (GLS) (NM_014905) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206265L4V
- LentiORF®
Lenti ORF particles, GLS (mGFP-tagged) - Human glutaminase (GLS), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | Glutaminase |
Synonyms | AAD20; CASGID; DEE71; EIEE71; GAC; GAM; GDPAG; GLS1; KGA |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_014905 |
ORF Size | 2007 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206265).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014905.2 |
RefSeq Size | 4799 bp |
RefSeq ORF | 2010 bp |
Locus ID | 2744 |
UniProt ID | O94925 |
Cytogenetics | 2q32.2 |
Domains | ANK, Glutaminase |
Protein Pathways | Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, D-Glutamine and D-glutamate metabolism, Metabolic pathways, Nitrogen metabolism |
MW | 73.3 kDa |
Gene Summary | This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
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