Asialoglycoprotein Receptor 1 (ASGR1) (NM_001671) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205686L4V

Lenti ORF particles, ASGR1 (mGFP-tagged) - Human asialoglycoprotein receptor 1 (ASGR1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Asialoglycoprotein Receptor 1
• Synonyms: ASGPR; ASGPR1; CLEC4H1; HL-1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001671
• ORF Size: 873 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205686).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001671.2
• RefSeq Size: 1519 bp
• RefSeq ORF: 876 bp
• Locus ID: 432
• UniProt ID: P07306
• Cytogenetics: 17p13.1
• Domains: CLECT, lectin_N
• Protein Families: Druggable Genome, Transmembrane
• MW: 33.2 kDa
• Gene Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]