Asialoglycoprotein Receptor 1 (ASGR1) (NM_001671) Human Tagged ORF Clone Lentiviral Particle

SKU RC205686L1V

Lenti ORF particles, ASGR1 (Myc-DDK tagged) - Human asialoglycoprotein receptor 1 (ASGR1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Asialoglycoprotein Receptor 1
• Synonyms: ASGPR; ASGPR1; CLEC4H1; HL-1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205686).
• ACCN: NM_001671
• ORF Size: 873 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001671.2
• RefSeq Size: 1519 bp
• RefSeq ORF: 876 bp
• Locus ID: 432
• UniProt ID: P07306
• Cytogenetics: 17p13.1
• Domains: CLECT, lectin_N
• Protein Families: Druggable Genome, Transmembrane
• MW: 33.2 kDa
• Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]