TJP2 (NM_004817) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205295L1V

Lenti ORF particles, TJP2 (Myc-DDK tagged) - Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TJP2
• Synonyms: C9DUPq21.11; DFNA51; DUP9q21.11; FHCA1; PFIC4; X104; ZO2
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_004817
• ORF Size: 3570 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205295).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004817.2
• RefSeq Size: 4618 bp
• RefSeq ORF: 3573 bp
• Locus ID: 9414
• UniProt ID: Q9UDY2
• Cytogenetics: 9q21.11
• Domains: SH3, PDZ, Guanylate_kin, GuKc
• Protein Pathways: Tight junction, Vibrio cholerae infection
• MW: 133.8 kDa
• Gene Summary: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]