TBK1 (NM_013254) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205238L2V

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  • LentiORF®

Lenti ORF particles, TBK1 (mGFP-tagged) - Human TANK-binding kinase 1 (TBK1), 200ul, >10^7 TU/mL



USD 1,218.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol TBK1
Synonyms FTDALS4; IIAE8; NAK; T2K
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_013254
ORF Size 2187 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC205238).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_013254.2
RefSeq Size 3098 bp
RefSeq ORF 2190 bp
Locus ID 29110
UniProt ID Q9UHD2
Cytogenetics 12q14.2
Domains pkinase, TyrKc, S_TKc
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
MW 83.6 kDa
Gene Summary The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
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