RSPO3 (NM_032784) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205016L4V

Lenti ORF particles, RSPO3 (mGFP-tagged) - Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: RSPO3
• Synonyms: CRISTIN1; PWTSR; THSD2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_032784
• ORF Size: 816 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205016).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032784.3
• RefSeq Size: 4583 bp
• RefSeq ORF: 819 bp
• Locus ID: 84870
• UniProt ID: Q9BXY4
• Cytogenetics: 6q22.33
• Domains: tsp_1, FU
• Protein Families: Druggable Genome, Secreted Protein
• MW: 30.9 kDa
• Gene Summary: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]