Claudin 3 (CLDN3) (NM_001306) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204882L4V

Lenti ORF particles, CLDN3 (mGFP-tagged) - Human claudin 3 (CLDN3), 200ul, >10^7 TU/mL

Product Images

RC204882L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC204882L4V particle to overexpress human CLDN3-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Claudin 3
• Synonyms: C7orf1; CPE-R2; CPETR2; HRVP1; RVP1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001306
• ORF Size: 660 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204882).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001306.2
• RefSeq Size: 1318 bp
• RefSeq ORF: 663 bp
• Locus ID: 1365
• UniProt ID: O15551
• Cytogenetics: 7q11.23
• Domains: PMP22_Claudin
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
• MW: 23.3 kDa
• Gene Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]