MUM1 (IRF4) (NM_002460) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC204876L2V
- LentiORF®
Lenti ORF particles, IRF4 (mGFP-tagged) - Human interferon regulatory factor 4 (IRF4), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | MUM1 |
Synonyms | LSIRF; MUM1; NF-EM5; SHEP8 |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_002460 |
ORF Size | 1353 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204876).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002460.1 |
RefSeq Size | 5332 bp |
RefSeq ORF | 1356 bp |
Locus ID | 3662 |
UniProt ID | Q15306 |
Cytogenetics | 6p25.3 |
Protein Families | Druggable Genome, Transcription Factors |
MW | 51.8 kDa |
Gene Summary | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] |
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