PAH (NM_000277) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204694L4V

Lenti ORF particles, PAH (mGFP-tagged) - Human phenylalanine hydroxylase (PAH), 200ul, >10^7 TU/mL

Product Images

RC204694L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC204694L4V particle to overexpress human PAH-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PAH
• Synonyms: PH; PKU; PKU1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_000277
• ORF Size: 1356 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204694).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000277.1, NP_000268.1
• RefSeq Size: 2680 bp
• RefSeq ORF: 1359 bp
• Locus ID: 5053
• UniProt ID: P00439
• Cytogenetics: 12q23.2
• Domains: biopterin_H, ACT
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Phenylalanine, tyrosine and tryptophan biosynthesis, Phenylalanine metabolism
• MW: 51.8 kDa
• Gene Summary: This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]