Fibroblast activation protein, alpha (FAP) (NM_004460) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204692L3V

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  • LentiORF®

Lenti ORF particles, FAP (Myc-DDK tagged) - Human fibroblast activation protein, alpha (FAP), 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
2 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol FAP
Synonyms DPPIV; FAPA; FAPalpha; SIMP
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_004460
ORF Size 2280 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204692).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_004460.2
RefSeq Size 2815 bp
RefSeq ORF 2283 bp
Locus ID 2191
UniProt ID Q12884
Cytogenetics 2q24.2
Domains Peptidase_S9, DPPIV_N_term
Protein Families Druggable Genome, Protease, Transmembrane
MW 87.7 kDa
Gene Summary The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
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