RAGE (AGER) (NM_001136) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204664L4V

Lenti ORF particles, AGER (mGFP-tagged) - Human advanced glycosylation end product-specific receptor (AGER), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC204664L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC204664L4V particle to overexpress human AGER-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: RAGE
• Synonyms: RAGE; SCARJ1; sRAGE
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001136
• ORF Size: 1212 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204664).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001136.3
• RefSeq Size: 1508 bp
• RefSeq ORF: 1215 bp
• Locus ID: 177
• UniProt ID: Q15109
• Cytogenetics: 6p21.32
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• MW: 42.8 kDa
• Gene Summary: The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]