BCL2 (NM_000633) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204498L4V

Lenti ORF particles, BCL2 (mGFP-tagged) - Human B-cell CLL/lymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, transcript variant alpha, 200ul, >10^7 TU/mL

Product Images

RC204498L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC204498L4V particle to overexpress human BCL2-mGFP fusion protein.

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  RC204498L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC204498L4V particle to overexpress human BCL2-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: BCL2
• Synonyms: Bcl-2; PPP1R50
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_000633
• ORF Size: 717 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204498).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000633.2
• RefSeq Size: 6492 bp
• RefSeq ORF: 720 bp
• Locus ID: 596
• UniProt ID: P10415
• Cytogenetics: 18q21.33
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer
• MW: 26.1 kDa
• Gene Summary: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]