IL11 (NM_000641) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204493L2V

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  • LentiORF®

Lenti ORF particles, IL11 (mGFP-tagged) - Human interleukin 11 (IL11), 200ul, >10^7 TU/mL



USD 850.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol IL11
Synonyms AGIF; IL-11
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_000641
ORF Size 597 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204493).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000641.2
RefSeq Size 2381 bp
RefSeq ORF 600 bp
Locus ID 3589
UniProt ID P20809
Cytogenetics 19q13.42
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
MW 21.4 kDa
Gene Summary The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
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