Kallikrein 7 (KLK7) (NM_005046) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204423L2V

Lenti ORF particles, KLK7 (mGFP-tagged) - Human kallikrein-related peptidase 7 (KLK7), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Kallikrein 7
• Synonyms: hK7; PRSS6; SCCE
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_005046
• ORF Size: 759 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204423).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005046.2
• RefSeq Size: 2104 bp
• RefSeq ORF: 762 bp
• Locus ID: 5650
• UniProt ID: P49862
• Cytogenetics: 19q13.41
• Protein Families: Druggable Genome, Secreted Protein
• MW: 27.6 kDa
• Gene Summary: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]