Frizzled 7 (FZD7) (NM_003507) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204167L4V

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  • LentiORF®

Lenti ORF particles, FZD7 (mGFP-tagged) - Human frizzled family receptor 7 (FZD7), 200ul, >10^7 TU/mL

  View "NM_003507" in other vectors (10)

USD 1,110.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name Frizzled 7 (FZD7) (NM_003507) Human Tagged ORF Clone Lentiviral Particle
Symbol FZD7
Synonyms FzE3
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_003507
ORF Size 1722 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204167).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_003507.1, NP_003498
RefSeq Size 3851
RefSeq ORF 1725
Locus ID 8324
Cytogenetics 2q33.1
Protein Families Druggable Genome, Transmembrane
Protein Pathways Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway
MW 63.4 kDa
Gene Summary Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

Other Versions

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