Frizzled 7(FZD7) (NM_003507) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204167L3V

  • LentiORF®

Lenti ORF particles, FZD7 (Myc-DDK tagged) - Human frizzled family receptor 7 (FZD7) , 200ul, >10^7 TU/mL

  View "NM_003507" in other vectors (10)

USD 1,000.00

2 Weeks

    • 200 ul

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Product Data
Product Name Frizzled 7(FZD7) (NM_003507) Human Tagged ORF Clone Lentiviral Particle
Symbol FZD7
Synonyms FzE3
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_003507
ORF Size 1722 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204167).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_003507.1, NP_003498
RefSeq Size 3851
RefSeq ORF 1725
Locus ID 8324
Cytogenetics 2q33.1
Protein Families Transmembrane, Druggable Genome
Protein Pathways Wnt signaling pathway, Melanogenesis, Pathways in cancer, Colorectal cancer, Basal cell carcinoma
MW 63.4 kDa
Gene Summary Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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