Superoxide Dismutase 3 (SOD3) (NM_003102) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204156L4V

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  • LentiORF®

Lenti ORF particles, SOD3 (mGFP-tagged) - Human superoxide dismutase 3, extracellular (SOD3), 200ul, >10^7 TU/mL


USD 820.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name Superoxide Dismutase 3 (SOD3) (NM_003102) Human Tagged ORF Clone Lentiviral Particle
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol SOD3
Synonyms EC-SOD
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
ACCN NM_003102
ORF Size 720 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204156).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_003102.2, NP_003093.1, NP_003093.2
RefSeq Size 1546
RefSeq ORF 723
Locus ID 6649
Cytogenetics 4p15.2
Domains sodcu
Protein Families Druggable Genome, Secreted Protein
MW 25.9 kDa
Gene Summary This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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