Retinoid X Receptor gamma (RXRG) (NM_006917) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204093L2V

Lenti ORF particles, RXRG (mGFP-tagged) - Human retinoid X receptor, gamma (RXRG), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Retinoid X Receptor gamma
• Synonyms: NR2B3; RXRC
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_006917
• ORF Size: 1389 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204093).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006917.3
• RefSeq Size: 2205 bp
• RefSeq ORF: 1392 bp
• Locus ID: 6258
• UniProt ID: P48443
• Cytogenetics: 1q23.3
• Domains: HOLI, zf-C4
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer
• MW: 50.9 kDa
• Gene Summary: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]