OB Cadherin (CDH11) (NM_001797) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203810L2V

Lenti ORF particles, CDH11 (mGFP-tagged) - Human cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: OB Cadherin
• Synonyms: CAD11; CDHOB; ESWS; OB; OSF-4
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001797
• ORF Size: 2388 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203810).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001797.2
• RefSeq Size: 3654 bp
• RefSeq ORF: 2391 bp
• Locus ID: 1009
• UniProt ID: P55287
• Cytogenetics: 16q21
• Domains: Cadherin_C_term, CA
• Protein Families: Druggable Genome, Transmembrane
• MW: 88 kDa
• Gene Summary: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]