Methionine Aminopeptidase 2 (METAP2) (NM_006838) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203809L2V

  • LentiORF®

Lenti ORF particles, METAP2 (mGFP-tagged) - Human methionyl aminopeptidase 2 (METAP2), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro

AAV Particle: DDK


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,007.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol Methionine Aminopeptidase 2
Synonyms MAP2; MNPEP; p67eIF2
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_006838
ORF Size 1434 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC203809).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_006838.3
RefSeq Size 3506 bp
RefSeq ORF 1437 bp
Locus ID 10988
UniProt ID P50579
Cytogenetics 12q22
Domains Peptidase_M24
Protein Families Druggable Genome, Protease
MW 52.7 kDa
Gene Summary The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

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