Dystrobrevin beta (DTNB) (NM_183361) Human Tagged ORF Clone Lentiviral Particle
SKU
RC203798L4V
Lenti ORF particles, DTNB (mGFP-tagged) - Human dystrobrevin, beta (DTNB), transcript variant 5, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Dystrobrevin beta |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203798).
|
ACCN | NM_183361 |
ORF Size | 1680 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_183361.1, NP_899205.1 |
RefSeq Size | 2328 bp |
RefSeq ORF | 1683 bp |
Locus ID | 1838 |
UniProt ID | O60941 |
Cytogenetics | 2p23.3 |
MW | 63.8 kDa |
Summary | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. [provided by RefSeq, Mar 2016] |
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