HBA-T2 (HBB) (NM_000518) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203258L2V

Lenti ORF particles, HBB (mGFP-tagged) - Human hemoglobin, beta (HBB), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: HBB
• Synonyms: beta-globin; CD113t-C; ECYT6
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000518
• ORF Size: 441 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203258).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000518.4
• RefSeq Size: 626 bp
• RefSeq ORF: 444 bp
• Locus ID: 3043
• UniProt ID: P68871
• Cytogenetics: 11p15.4
• Domains: globin
• MW: 16 kDa
• Gene Summary: The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]