IMPDH2 (NM_000884) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202977L2V

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  • LentiORF®

Lenti ORF particles, IMPDH2 (mGFP-tagged) - Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), 200ul, >10^7 TU/mL



USD 1,029.00

6 Weeks*

Size
    • 200 ul

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Frequently bought together (2)
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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol IMPDH2
Synonyms IMPD2; IMPDH-II
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_000884
ORF Size 1542 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC202977).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000884.2
RefSeq Size 1712 bp
RefSeq ORF 1545 bp
Locus ID 3615
UniProt ID P12268
Cytogenetics 3p21.31
Domains CBS, IMPDH
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
MW 55.8 kDa
Gene Summary This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.