LKB1 (STK11) (NM_000455) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202885L4V

Lenti ORF particles, STK11 (mGFP-tagged) - Human serine/threonine kinase 11 (STK11), 200ul, >10^7 TU/mL

Product Images

RC202885L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC202885L4V particle to overexpress human STK11-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: LKB1
• Synonyms: hLKB1; LKB1; PJS
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_000455
• ORF Size: 1299 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202885).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000455.4
• RefSeq Size: 3286 bp
• RefSeq ORF: 1302 bp
• Locus ID: 6794
• UniProt ID: Q15831
• Cytogenetics: 19p13.3
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adipocytokine signaling pathway, mTOR signaling pathway
• MW: 48.5 kDa
• Gene Summary: This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]