TNFAIP8 (NM_014350) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202729L2V

Lenti ORF particles, TNFAIP8 (mGFP-tagged) - Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TNFAIP8
• Synonyms: GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_014350
• ORF Size: 594 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202729).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014350.2
• RefSeq Size: 2103 bp
• RefSeq ORF: 597 bp
• Locus ID: 25816
• UniProt ID: O95379
• Cytogenetics: 5q23.1
• Protein Families: Druggable Genome
• MW: 23 kDa
• Gene Summary: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.[UniProtKB/Swiss-Prot Function]