VKORC1 (NM_024006) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202639L3V

  • LentiORF®

Lenti ORF particles, VKORC1 (Myc-DDK tagged) - Human vitamin K epoxide reductase complex, subunit 1 (VKORC1), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro

AAV Particle: DDK


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 700.00

5 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol VKORC1
Synonyms EDTP308; MST134; MST576; VKCFD2; VKOR
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_024006
ORF Size 489 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC202639).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_024006.4
RefSeq Size 1042 bp
RefSeq ORF 492 bp
Locus ID 79001
UniProt ID Q9BQB6
Cytogenetics 16p11.2
Protein Families Transmembrane
MW 18.2 kDa
Gene Summary This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

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