GM2A (NM_000405) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202452L4V
- LentiORF®
Lenti ORF particles, GM2A (mGFP-tagged) - Human GM2 ganglioside activator (GM2A), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
AAV Particle: DDK
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | GM2A |
Synonyms | GM2-AP; SAP-3 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_000405 |
ORF Size | 579 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202452).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000405.3 |
RefSeq Size | 3690 bp |
RefSeq ORF | 582 bp |
Locus ID | 2760 |
UniProt ID | P17900 |
Cytogenetics | 5q33.1 |
Domains | ML |
Protein Families | Druggable Genome |
Protein Pathways | Lysosome |
MW | 20.8 kDa |
Gene Summary | This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] |
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