SUV39H1 (NM_003173) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202428L2V

Lenti ORF particles, SUV39H1 (mGFP-tagged) - Human suppressor of variegation 3-9 homolog 1 (Drosophila) (SUV39H1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SUV39H1
• Synonyms: H3-K9-HMTase 1; KMT1A; MG44; SUV39H
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003173
• ORF Size: 1236 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202428).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003173.2
• RefSeq Size: 2752 bp
• RefSeq ORF: 1239 bp
• Locus ID: 6839
• UniProt ID: O43463
• Cytogenetics: Xp11.23
• Domains: CHROMO, SET, PreSET, PostSET, Pre-SET
• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation
• MW: 47.9 kDa
• Gene Summary: This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]