TWSG1 (NM_020648) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202337L1V

Lenti ORF particles, TWSG1 (Myc-DDK tagged) - Human twisted gastrulation homolog 1 (Drosophila) (TWSG1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: TWSG1
• Synonyms: TSG
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_020648
• ORF Size: 669 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202337).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020648.3
• RefSeq Size: 3779 bp
• RefSeq ORF: 672 bp
• Locus ID: 57045
• UniProt ID: Q9GZX9
• Cytogenetics: 18p11.22
• Domains: Tsg
• MW: 25 kDa
• Gene Summary: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).[UniProtKB/Swiss-Prot Function]