IFI16 (NM_005531) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202193L4V

Lenti ORF particles, IFI16 (mGFP-tagged) - Human interferon, gamma-inducible protein 16 (IFI16), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: IFI16
• Synonyms: IFNGIP1; PYHIN2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005531
• ORF Size: 2187 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202193).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005531.1, NP_005522.1
• RefSeq Size: 2709 bp
• RefSeq ORF: 2190 bp
• Locus ID: 3428
• UniProt ID: Q16666
• Cytogenetics: 1q23.1
• Domains: PAAD_DAPIN, HIN
• Protein Families: Transcription Factors
• MW: 81.9 kDa
• Gene Summary: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]