CORD2 (CRX) (NM_000554) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202160L2V

Lenti ORF particles, CRX (mGFP-tagged) - Human cone-rod homeobox (CRX), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CORD2
• Synonyms: CORD2; CRD; LCA7; OTX3
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000554
• ORF Size: 897 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202160).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000554.2
• RefSeq Size: 4482 bp
• RefSeq ORF: 900 bp
• Locus ID: 1406
• UniProt ID: O43186
• Cytogenetics: 19q13.33
• Protein Families: Druggable Genome, Transcription Factors
• MW: 32.3 kDa
• Gene Summary: The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]