TRIM21 (NM_003141) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202088L2V

Lenti ORF particles, TRIM21 (mGFP-tagged) - Human tripartite motif containing 21 (TRIM21), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TRIM21
• Synonyms: RNF81; Ro/SSA; RO52; SSA; SSA1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003141
• ORF Size: 1425 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202088).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003141.3
• RefSeq Size: 1946 bp
• RefSeq ORF: 1428 bp
• Locus ID: 6737
• UniProt ID: P19474
• Cytogenetics: 11p15.4
• Domains: zf-B_box, RING, SPRY, PRY
• Protein Families: Druggable Genome
• Protein Pathways: Systemic lupus erythematosus
• MW: 54.2 kDa
• Gene Summary: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]