IL1 alpha (IL1A) (NM_000575) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202084L2V

Lenti ORF particles, IL1A (mGFP-tagged) - Human interleukin 1, alpha (IL1A), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: IL1 alpha
• Synonyms: IL-1 alpha; IL-1A; IL1; IL1-ALPHA; IL1F1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_000575
• ORF Size: 813 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202084).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000575.3
• RefSeq Size: 2943 bp
• RefSeq ORF: 816 bp
• Locus ID: 3552
• UniProt ID: P01583
• Cytogenetics: 2q14.1
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus
• MW: 30.6 kDa
• Gene Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]