Noxa (PMAIP1) (NM_021127) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202071L2V

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  • LentiORF®

Lenti ORF particles, PMAIP1 (mGFP-tagged) - Human phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
6 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol PMAIP1
Synonyms APR; NOXA
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_021127
ORF Size 162 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC202071).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_021127.1
RefSeq Size 1885 bp
RefSeq ORF 165 bp
Locus ID 5366
UniProt ID Q13794
Cytogenetics 18q21.32
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways p53 signaling pathway
MW 5.8 kDa
Gene Summary This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response to death-inducing stimuli, BH3-only members inhibit the anti-apoptotic BCL-2 family members, which under steady-state conditions keep the multi-BH domain proteins BAX and BAK, in an inactive state. [provided by RefSeq, Aug 2020]
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