NCKAP1 (NM_013436) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201960L2V

Lenti ORF particles, NCKAP1 (mGFP-tagged) - Human NCK-associated protein 1 (NCKAP1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: NCKAP1
• Synonyms: HEM2; NAP1; NAP125; p125Nap1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_013436
• ORF Size: 3384 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201960).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013436.3
• RefSeq Size: 4997 bp
• RefSeq ORF: 3387 bp
• Locus ID: 10787
• UniProt ID: Q9Y2A7
• Cytogenetics: 2q32.1
• Protein Families: Druggable Genome
• Protein Pathways: Regulation of actin cytoskeleton
• MW: 128.8 kDa
• Gene Summary: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.[UniProtKB/Swiss-Prot Function]