Aquaporin 3 (AQP3) (NM_004925) Human Tagged ORF Clone Lentiviral Particle
SKU
RC201856L4V
Lenti ORF particles, AQP3 (mGFP-tagged) - Human aquaporin 3 (Gill blood group) (AQP3), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Aquaporin 3 |
Synonyms | AQP-3; GIL |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC201856).
|
ACCN | NM_004925 |
ORF Size | 876 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_004925.3 |
RefSeq Size | 1882 bp |
RefSeq ORF | 879 bp |
Locus ID | 360 |
UniProt ID | Q92482 |
Cytogenetics | 9p13.3 |
Domains | MIP |
Protein Families | Druggable Genome, Transmembrane |
MW | 31.5 kDa |
Summary | This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
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