Beclin 1 (BECN1) (NM_003766) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201629L2V

Lenti ORF particles, BECN1 (mGFP-tagged) - Human beclin 1, autophagy related (BECN1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Beclin 1
• Synonyms: ATG6; beclin1; VPS30
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003766
• ORF Size: 1350 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201629).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003766.2
• RefSeq Size: 2144 bp
• RefSeq ORF: 1353 bp
• Locus ID: 8678
• UniProt ID: Q14457
• Cytogenetics: 17q21.31
• Domains: APG6
• Protein Families: Druggable Genome
• Protein Pathways: Regulation of autophagy
• MW: 51.7 kDa
• Gene Summary: This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]