SH3 containing Grb 2 like 1 protein (SH3GL1) (NM_003025) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201552L2V

Lenti ORF particles, SH3GL1 (mGFP-tagged) - Human SH3-domain GRB2-like 1 (SH3GL1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SH3 containing Grb 2 like 1 protein
• Synonyms: CNSA1; EEN; SH3D2B; SH3P8
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003025
• ORF Size: 1104 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201552).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003025.2, NP_003016.1
• RefSeq Size: 2559 bp
• RefSeq ORF: 1107 bp
• Locus ID: 6455
• UniProt ID: Q99961
• Cytogenetics: 19p13.3
• Domains: SH3, BAR
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• MW: 41.5 kDa
• Gene Summary: This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]