PAMM (FAM213A) (NM_032333) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201327L2V

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  • LentiORF®

Lenti ORF particles, FAM213A (mGFP-tagged) - Human chromosome 10 open reading frame 58 (C10orf58), transcript variant 1, 200ul, >10^7 TU/mL



USD 850.00

6 Weeks*

Size
    • 200 ul

Product images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol PRXL2A
Synonyms Adrx; C10orf58; FAM213A; PAMM
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_032333
ORF Size 687 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC201327).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_032333.2
RefSeq Size 1690 bp
RefSeq ORF 690 bp
Locus ID 84293
UniProt ID Q9BRX8
Cytogenetics 10q23.1
Protein Families Secreted Protein, Transmembrane
MW 25.6 kDa
Gene Summary Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880).[UniProtKB/Swiss-Prot Function]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.