n-Myc (MYCN) (NM_005378) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201241L4V

Lenti ORF particles, MYCN (mGFP-tagged) - Human v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: n-Myc
• Synonyms: bHLHe37; MODED; N-myc; NMYC; ODED
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005378
• ORF Size: 1392 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201241).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005378.4
• RefSeq Size: 2736 bp
• RefSeq ORF: 1395 bp
• Locus ID: 4613
• UniProt ID: P04198
• Cytogenetics: 2p24.3
• Domains: HLH, Myc_N_term
• Protein Families: Druggable Genome, Transcription Factors
• MW: 49.6 kDa
• Gene Summary: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]