NCF1 (NM_000265) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201233L1V
- LentiORF®
Lenti ORF particles, NCF1 (Myc-DDK tagged) - Human neutrophil cytosolic factor 1 (NCF1), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro mGFP mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | NCF1 |
Synonyms | CGD1; NCF1A; NOXO2; p47phox; SH3PXD1A |
Mammalian Cell Selection | None |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_000265 |
ORF Size | 1170 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201233).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000265.4 |
RefSeq Size | 1409 bp |
RefSeq ORF | 1173 bp |
Locus ID | 653361 |
UniProt ID | P14598 |
Cytogenetics | 7q11.23 |
Domains | SH3, PX |
Protein Pathways | Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton |
MW | 44.5 kDa |
Gene Summary | The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008] |
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