SSX2 (NM_003147) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201214L4V

Lenti ORF particles, SSX2 (mGFP-tagged) - Human synovial sarcoma, X breakpoint 2 (SSX2), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC201214L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC201214L4V particle to overexpress human SSX2-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SSX2
• Synonyms: CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_003147
• ORF Size: 669 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201214).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003147.4
• RefSeq Size: 1494 bp
• RefSeq ORF: 672 bp
• Locus ID: 6757
• UniProt ID: Q16385
• Cytogenetics: Xp11.22
• Protein Families: Druggable Genome, Transcription Factors
• MW: 25.2 kDa
• Gene Summary: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013]